Feb 02, 2022 · Longterm estivation (45 days) in the apple snail Pomacea canaliculata induces an increase of nonenzymatic antioxidants, such as uric acid and reduced glutathione (GSH), which constitutes an alternative to the adaptive physiological strategy of preparation for oxidative stress (POS). Here, we studied markers of oxidative stress damage, uric acid levels, and non .